Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 6/20 | 0.35 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 4/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30984964 | 0.92 | CYP3A4 (0.36) | JAK2TRPC5ALDH1A1KDM4EMAPT | |
| SCHEMBL30985228 | 0.87 | SYK (0.38) | JAK2ALDH1A1KDM4EMAPTCYP3A4 | |
| SCHEMBL30984790 | 0.76 | CRBN (0.41) | — | |
| SCHEMBL25937317 | 0.74 | HSD17B10 (0.53) | ALDH1A1KDM4EMAPTMEN1POLB | |
| SCHEMBL30985209 | 0.73 | CYP11B2 (0.56) | PARP1 | |
| SCHEMBL30984996 | 0.70 | MEN1 (0.45) | JAK2ALDH1A1MAPTCYP3A4MEN1 | |
| SCHEMBL31204379 | 0.69 | SIRT6 (0.40) | ALDH1A1MAPTCYP3A4MEN1KMT2A | |
| SCHEMBL30985122 | 0.68 | PARP1 (0.38) | JAK2ALDH1A1CYP3A4PARP1PRKCI | |
| SCHEMBL25141632 | 0.68 | MAPT (0.48) | ALDH1A1MAPTCYP3A4MEN1KMT2A | |
| SCHEMBL27041920 | 0.67 | POLB (0.38) | ALDH1A1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |