Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 10/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30987027 | 0.87 | RORC (0.41) | RORCUSP2SMN1; SMN2RECQLNR1H2 | |
| SCHEMBL30987087 | 0.87 | RORC (0.41) | RORCUSP2SMN1; SMN2RECQLNR1H2 | |
| SCHEMBL30987170 | 0.87 | RORC (0.41) | RORCUSP2SMN1; SMN2RECQLNR1H2 | |
| SCHEMBL30987177 | 0.81 | NR1H2 (0.43) | RORCUSP2SMN1; SMN2PDK1RECQL | |
| SCHEMBL30987199 | 0.80 | MAPT (0.40) | RORCUSP2SMN1; SMN2RECQLNR1H2 | |
| SCHEMBL194709 | 0.79 | USP2 (0.54) | USP2SMN1; SMN2PDK1RECQLNR1H2 | |
| SCHEMBL194710 | 0.79 | USP2 (0.54) | USP2SMN1; SMN2PDK1RECQLNR1H2 | |
| SCHEMBL59641 | 0.79 | USP2 (0.54) | USP2SMN1; SMN2PDK1RECQLNR1H2 | |
| SCHEMBL25869375 | 0.79 | RORC (0.39) | RORCUSP2SMN1; SMN2RECQLNR1H2 | |
| SCHEMBL30987036 | 0.79 | USP2 (0.38) | RORCUSP2SMN1; SMN2PDK1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4646265-A1 | NOVEL, REVERSIBLE DPP1 INHIBITORS AND USES THEREOF | Insmed Incorporated (US) | 2025-11-12 | — | — | EP | disclosed |
| WO-2024148308-A1 | NOVEL, REVERSIBLE DPP1 INHIBITORS AND USES THEREOF | INSMED INCORPORATED (US) | 2024-07-11 | — | — | WO | disclosed |