Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30987027 | 0.87 | RORC (0.41) | MAPTMEN1ALDH1A1KMT2AUSP2 | |
| SCHEMBL30987170 | 0.87 | RORC (0.41) | MAPTMEN1ALDH1A1KMT2AUSP2 | |
| SCHEMBL30987087 | 0.87 | RORC (0.41) | MAPTMEN1ALDH1A1KMT2AUSP2 | |
| SCHEMBL30987197 | 0.81 | NR1H2 (0.43) | MAPTMEN1ALDH1A1KMT2AUSP2 | |
| SCHEMBL30987166 | 0.80 | RORC (0.40) | MAPTMEN1ALDH1A1KMT2AUSP2 | |
| SCHEMBL59641 | 0.79 | USP2 (0.54) | MAPTMEN1ALDH1A1KMT2AUSP2 | |
| SCHEMBL194709 | 0.79 | USP2 (0.54) | MAPTMEN1ALDH1A1KMT2AUSP2 | |
| SCHEMBL194710 | 0.79 | USP2 (0.54) | MAPTMEN1ALDH1A1KMT2AUSP2 | |
| SCHEMBL25869375 | 0.79 | RORC (0.39) | MAPTMEN1ALDH1A1KMT2AUSP2 | |
| SCHEMBL29295638 | 0.77 | HSD17B10 (0.38) | ALDH1A1USP2SMN1; SMN2RECQLNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4646265-A1 | NOVEL, REVERSIBLE DPP1 INHIBITORS AND USES THEREOF | Insmed Incorporated (US) | 2025-11-12 | — | — | EP | disclosed |
| WO-2024148308-A1 | NOVEL, REVERSIBLE DPP1 INHIBITORS AND USES THEREOF | INSMED INCORPORATED (US) | 2024-07-11 | — | — | WO | disclosed |