Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.45 |
| ▸ | RARA | P10276 | 8/20 | 0.45 |
| ▸ | RARG | P13631 | 7/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | POLQ | O75417 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | CTSC | P53634 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27272881 | 1.00 | RARB (0.45) | RARBRARARARGSLC22A12POLQ | |
| SCHEMBL30987741 | 0.89 | HCAR2 (0.42) | HCAR2AOC3 | |
| SCHEMBL27272895 | 0.89 | HCAR2 (0.42) | HCAR2AOC3 | |
| SCHEMBL30987780 | 0.85 | CTSK (0.43) | POLQAOC3CTSKCTSC | |
| SCHEMBL27272844 | 0.85 | CTSK (0.43) | POLQAOC3CTSKCTSC | |
| SCHEMBL2408026 | 0.80 | AOC3 (0.45) | AOC3CTSKCTSC | |
| SCHEMBL24271748 | 0.79 | ACMSD (0.54) | SLC22A12 | |
| SCHEMBL27272866 | 0.77 | GSK3B (0.40) | POLQAOC3CTSKCTSC | |
| SCHEMBL30987637 | 0.77 | GSK3B (0.40) | POLQAOC3CTSKCTSC | |
| SCHEMBL19368051 | 0.77 | CTSK (0.46) | AOC3ALOX5APFEN1CTSKCTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676929-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | Dark Blue Therapeutics Ltd (GB) | 2026-01-14 | — | — | EP | disclosed |
| EP-4638447-A1 | IMIDAZO[1,2-A]PYRIDINE AND IMIDAZO[1,2-A]PYRAZINE DERIVATIVES AS MLLT1 AND MLLT3 INHIBITORS | Dark Blue Therapeutics Ltd (GB) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024188906-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | DARK BLUE THERAPEUTICS LTD (GB) | 2024-09-19 | — | — | WO | disclosed |
| WO-2024133560-A1 | IMIDAZO[1,2-A]PYRIDINE AND IMIDAZO[1,2-A]PYRAZINE DERIVATIVES AS MLLT1 AND MLLT3 INHIBITORS | DARK BLUE THERAPEUTICS LTD (GB) | 2024-06-27 | — | — | WO | disclosed |