Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROR1 | Q01973 | 11/20 | 0.81 |
| ▸ | CSF1R | P07333 | 2/20 | 0.68 |
| ▸ | ABL1 | P00519 | 8/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.64 |
| ▸ | GAK | O14976 | 1/20 | 0.63 |
| ▸ | MLNR | O43193 | 1/20 | 0.63 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.63 |
| ▸ | JAK2 | O60674 | 1/20 | 0.63 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.63 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.63 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.63 |
| ▸ | EGFR | P00533 | 1/20 | 0.63 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.63 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.63 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.63 |
| ▸ | LCK | P06239 | 1/20 | 0.63 |
| ▸ | FYN | P06241 | 1/20 | 0.63 |
| ▸ | PGR | P06401 | 1/20 | 0.63 |
| ▸ | YES1 | P07947 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30987917 | 0.89 | ROR1 (1.00) | ROR1CSF1RABL1 | |
| SCHEMBL30987915 | 0.86 | ROR1 (0.75) | ROR1CSF1RABL1CYP3A4KCNH2 | |
| SCHEMBL16640183 | 0.86 | ROR1 (0.94) | ROR1CSF1RABL1ABL2 | |
| SCHEMBL19317721 | 0.85 | ROR1 (0.79) | ROR1CSF1RABL1CYP3A4KCNH2 | |
| SCHEMBL16644466 | 0.84 | CSF1R (0.75) | ROR1CSF1RABL1CYP3A4KCNH2 | |
| SCHEMBL16250614 | 0.83 | ABL1 (0.80) | ROR1CSF1RABL1CYP3A4KCNH2 | |
| SCHEMBL22559533 | 0.83 | ABL1 (0.78) | ROR1CSF1RABL1CYP3A4KCNH2 | |
| SCHEMBL22559443 | 0.83 | ABL1 (0.78) | ROR1CSF1RABL1CYP3A4KCNH2 | |
| SCHEMBL12682241 | 0.82 | ROR1 (0.72) | ROR1CSF1RABL1CYP3A4KCNH2 | |
| SCHEMBL16644588 | 0.82 | ABL1 (0.76) | ROR1CSF1RABL1CYP3A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118406057-A | 4-Methylbenzamide compound and application thereof | 四川大学 | 2024-07-30 | — | — | CN | disclosed |