Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.43 |
| ▸ | EIF4E | P06730 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30988467 | 0.90 | IRAK4 (0.48) | MKNK1MKNK2PIM1PIM2ROCK1 | |
| SCHEMBL31704583 | 0.77 | KIT (0.46) | MKNK1MKNK2EIF4EMAPK1BRD4 | |
| SCHEMBL30988449 | 0.76 | MEN1 (0.40) | MEN1KMT2APOLBMAPTTNIK | |
| SCHEMBL30988461 | 0.76 | TNIK (0.41) | BRD4CREBBPPIM1MEN1KMT2A | |
| SCHEMBL26135323 | 0.71 | BRD4 (0.45) | MKNK1MKNK2EIF4EBRD4CREBBP | |
| SCHEMBL31457959 | 0.71 | BRD4 (0.45) | MKNK1MKNK2EIF4EBRD4CREBBP | |
| SCHEMBL73351 | 0.69 | MEN1 (0.53) | MEN1KMT2APOLBMAPT | |
| SCHEMBL21033314 | 0.69 | BRD4 (0.41) | MKNK1MKNK2EIF4EBRD4CREBBP | |
| SCHEMBL69492 | 0.69 | MEN1 (0.58) | MEN1KMT2APOLBMAPT | |
| SCHEMBL31705955 | 0.69 | MKNK1 (0.52) | MKNK1MKNK2EIF4EMAPK1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324752-A | Five-membered heterocyclic compound with phenyl substitution, and preparation and application thereof | 江西中医药大学 | 2024-07-12 | — | — | CN | disclosed |