Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.46 |
| ▸ | EIF4E | P06730 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | TET3 | O43151 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL31704516 | 0.88 | KIT (0.45) | KITBRD4MKNK1MKNK2EIF4E | |
| Lithium Ion SCHEMBL31705351 | 0.88 | KIT (0.45) | KITBRD4MKNK1MKNK2EIF4E | |
| SCHEMBL31165946 | 0.86 | GRK5 (0.46) | BRD4MKNK1MKNK2EIF4EPIM1 | |
| SCHEMBL31706532 | 0.85 | MKNK1 (0.48) | KITBRD4MKNK1MKNK2EIF4E | |
| SCHEMBL31706350 | 0.85 | MKNK1 (0.48) | KITBRD4MKNK1MKNK2EIF4E | |
| SCHEMBL30988451 | 0.77 | MKNK1 (0.43) | KITBRD4MKNK1MKNK2EIF4E | |
| SCHEMBL29479792 | 0.76 | GRK5 (0.51) | PIM1PIM2 | |
| SCHEMBL28713867 | 0.76 | GRK5 (0.51) | PIM1PIM2 | |
| SCHEMBL21033314 | 0.76 | BRD4 (0.41) | KITBRD4MKNK1MKNK2EIF4E | |
| SCHEMBL31705955 | 0.75 | MKNK1 (0.52) | KITBRD4MKNK1MKNK2EIF4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |