Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30988449 | 0.79 | MEN1 (0.40) | TNIKMEN1KMT2AMAPTPOLB | |
| SCHEMBL30988451 | 0.76 | MKNK1 (0.43) | TNIKMEN1KMT2AMAPTPOLB | |
| SCHEMBL30988467 | 0.74 | IRAK4 (0.48) | TNIKMEN1KMT2AMAPTPOLB | |
| SCHEMBL29114953 | 0.73 | KMO (0.52) | MEN1KMT2AMAPTPOLBHCAR2 | |
| SCHEMBL30683711 | 0.73 | KMO (0.52) | MEN1KMT2AMAPTPOLBHCAR2 | |
| SCHEMBL73351 | 0.72 | MEN1 (0.53) | MEN1KMT2AMAPTPOLBHCAR2 | |
| SCHEMBL69492 | 0.72 | MEN1 (0.58) | MEN1KMT2AMAPTPOLBHCAR2 | |
| SCHEMBL31131781 | 0.72 | HCAR2 (0.45) | TNIKMEN1KMT2AMAPTPOLB | |
| Hydrochloric Acid SCHEMBL1221862 | 0.70 | MEN1 (0.57) | MEN1KMT2AMAPTPOLBHCAR2 | |
| SCHEMBL18086771 | 0.70 | PDK2 (0.47) | MEN1KMT2AMAPTBRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324752-A | Five-membered heterocyclic compound with phenyl substitution, and preparation and application thereof | 江西中医药大学 | 2024-07-12 | — | — | CN | disclosed |