Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15729475 | 0.89 | ATM (0.54) | ATMKMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL30988969 | 0.88 | SMN1; SMN2 (0.49) | KMT2AMEN1L3MBTL1MAPTGAA | |
| SCHEMBL10906074 | 0.86 | ATM (0.62) | ATML3MBTL1ALDH1A1THRBCYP2C9 | |
| SCHEMBL28406623 | 0.86 | CASP1 (0.50) | MAPTGAATRPM8MEP1BALDH1A1 | |
| SCHEMBL26130291 | 0.86 | CASP1 (0.50) | MAPTGAATRPM8MEP1BALDH1A1 | |
| SCHEMBL14636601 | 0.85 | ATM (0.56) | ATMKMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL304265 | 0.85 | ATM (0.56) | ATMKMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL7907847 | 0.85 | ATM (0.56) | ATMKMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL2375644 | 0.85 | ATM (0.68) | ATMKMT2AMEN1L3MBTL1GAA | |
| SCHEMBL5878196 | 0.85 | ATM (0.56) | ATMKMT2AMEN1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097744-A2 | DNA-COMPATIBLE WITTIG OLEFINATION OF ON-DNA PEPTIDYL-YLIDES FOR DEVELOPMENT OF ON-DNA PEPTIDOMIMETICS THROUGH DIVERSITY-ORIENTED SYNTHESIS (DOS) | THE ROCKEFELLER UNIVERSITY (US) | 2024-05-10 | — | — | WO | disclosed |