Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 4/20 | 0.47 |
| ▸ | MMP13 | P45452 | 5/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 3/20 | 0.45 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1499947 | 0.88 | MMP2 (0.50) | MMP13SLC1A3SLC1A2SLC1A1MMP2 | |
| SCHEMBL28554116 | 0.85 | GAA (0.55) | TDP1MMP13ADAMTS4SLC1A3SLC1A2 | |
| SCHEMBL30988968 | 0.85 | GAA (0.55) | TDP1MMP13ADAMTS4SLC1A3SLC1A2 | |
| SCHEMBL698842 | 0.82 | TDP1 (0.63) | TDP1MMP13ADAMTS4SLC1A3SLC1A2 | |
| SCHEMBL4339865 | 0.82 | TDP1 (0.63) | TDP1MMP13ADAMTS4SLC1A3SLC1A2 | |
| SCHEMBL698843 | 0.82 | TDP1 (0.63) | TDP1MMP13ADAMTS4SLC1A3SLC1A2 | |
| SCHEMBL4172106 | 0.82 | TDP1 (0.54) | TDP1PSMB8MMP13PSMB5ADAMTS4 | |
| SCHEMBL29196180 | 0.81 | MMP2 (0.49) | TDP1MMP13SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7692231 | 0.80 | TDP1 (0.49) | TDP1PSMB8MMP13PSMB5ADAMTS4 | |
| SCHEMBL8445714 | 0.79 | MMP2 (0.64) | TDP1MMP13ADAMTS4MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097744-A2 | DNA-COMPATIBLE WITTIG OLEFINATION OF ON-DNA PEPTIDYL-YLIDES FOR DEVELOPMENT OF ON-DNA PEPTIDOMIMETICS THROUGH DIVERSITY-ORIENTED SYNTHESIS (DOS) | THE ROCKEFELLER UNIVERSITY (US) | 2024-05-10 | — | — | WO | disclosed |