Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | MMP2 | P08253 | 9/20 | 0.57 |
| ▸ | MMP13 | P45452 | 5/20 | 0.57 |
| ▸ | MMP3 | P08254 | 3/20 | 0.57 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.56 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.56 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 9/20 | 0.55 |
| ▸ | MMP1 | P03956 | 3/20 | 0.55 |
| ▸ | MMP7 | P09237 | 2/20 | 0.55 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.54 |
| ▸ | MMP8 | P22894 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698842 | 1.00 | TDP1 (0.63) | TDP1MMP2MMP13MMP3SLC1A3 | |
| SCHEMBL698843 | 1.00 | TDP1 (0.63) | TDP1MMP2MMP13MMP3SLC1A3 | |
| SCHEMBL5189409 | 0.88 | TDP1 (0.60) | TDP1MMP2MMP13MMP3SLC1A3 | |
| SCHEMBL4041026 | 0.88 | TDP1 (0.60) | TDP1MMP2MMP13MMP3SLC1A3 | |
| SCHEMBL10967894 | 0.88 | TDP1 (0.60) | TDP1MMP2MMP13MMP3SLC1A3 | |
| SCHEMBL11571551 | 0.86 | TDP1 (0.55) | TDP1MMP2MMP13MMP3SLC1A3 | |
| SCHEMBL3392197 | 0.86 | TDP1 (0.64) | TDP1MMP2MMP13MMP3SLC1A3 | |
| SCHEMBL3427026 | 0.86 | TDP1 (0.64) | TDP1MMP2MMP13MMP3SLC1A3 | |
| SCHEMBL1734695 | 0.86 | TDP1 (0.64) | TDP1MMP2MMP13MMP3SLC1A3 | |
| SCHEMBL5193396 | 0.86 | TDP1 (0.64) | TDP1MMP2MMP13MMP3SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569690-B2 | Process for producing oxycarbonyl-substituted piperazine derivative | TORAY FINE CHEMICALS CO., LTD. (JP) | 2009-08-04 | — | — | US | disclosed |
| CN-100360510-C | Process for producing oxycarbonyl-substituted piperazine derivative | TORAY FINECHEMICALS CO LTD (JP) | 2008-01-09 | — | — | CN | disclosed |
| US-20060161003-A1 | Process for producing oxycarbonyl-substituted piperazine derivative | TORAY FINE CHEMICALS CO., LTD. (JP) | 2006-07-20 | — | — | US | disclosed |
| CN-1681797-A | Process for producing oxycarbonyl-substituted piperazine derivative | TORAY FINECHEMICALS CO LTD (JP) | 2005-10-12 | — | — | CN | disclosed |
| EP-1548010-A1 | PROCESS FOR PRODUCING OXYCARBONYL-SUBSTITUTED PIPERAZINE DERIVATIVE | Toray Fine Chemicals Co., Ltd. (JP) | 2005-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060161003-A1 | Process for producing oxycarbonyl-substituted piperazine derivative | DHPS, AQP4, OGFOD1 | TDP1 4105/4885MMP2 458/4885MMP13 543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.