Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25205310 | 1.00 | GPR119 (0.41) | GPR119USP30NR1H2HPGDRORC | |
| SCHEMBL30424375 | 0.79 | USP30 (0.42) | GPR119USP30RORCPOLB | |
| SCHEMBL25213032 | 0.79 | USP30 (0.42) | GPR119USP30RORCPOLB | |
| SCHEMBL25888712 | 0.78 | PDE10A (0.49) | GPR119NR1H2RORCPOLB | |
| SCHEMBL31655333 | 0.78 | PDE10A (0.49) | GPR119NR1H2RORCPOLB | |
| SCHEMBL23802301 | 0.78 | GPR119 (0.51) | GPR119USP30NR1H2HPGDRORC | |
| SCHEMBL25212055 | 0.74 | GPR119 (0.40) | GPR119NR1H2RORCPOLB | |
| SCHEMBL30989288 | 0.74 | GPR119 (0.40) | GPR119NR1H2RORCPOLB | |
| SCHEMBL21381625 | 0.74 | HSD11B1 (0.48) | USP30SMN1; SMN2 | |
| SCHEMBL1528737 | 0.74 | HDAC1 (0.42) | USP30NR1H2HPGDRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118302411-A | Therapeutic indazole compounds and methods of use thereof for the treatment of cancer | 基因泰克公司 | 2024-07-05 | — | — | CN | disclosed |