Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 4/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25885994 | 1.00 | POLB (0.33) | POLBGRIN1GRIN2BRORCDGAT1 | |
| SCHEMBL30989728 | 0.95 | POLB (0.39) | POLBGRIN1GRIN2BDGAT1 | |
| SCHEMBL25885629 | 0.95 | POLB (0.39) | POLBGRIN1GRIN2BDGAT1 | |
| SCHEMBL25885639 | 0.93 | POLB (0.33) | POLBGRIN1GRIN2BRORC | |
| SCHEMBL31081718 | 0.88 | PIM1 (0.33) | POLBGRIN1GRIN2B | |
| SCHEMBL25437550 | 0.88 | RORC (0.33) | GRIN1GRIN2BRORCDGAT1 | |
| SCHEMBL30989689 | 0.88 | RORC (0.33) | GRIN1GRIN2BRORCDGAT1 | |
| SCHEMBL30989653 | 0.87 | BRD4 (0.31) | GRIN1GRIN2BRORCBRD4 | |
| SCHEMBL25885742 | 0.87 | BRD4 (0.31) | GRIN1GRIN2BRORCBRD4 | |
| SCHEMBL25886057 | 0.87 | DGAT1 (0.31) | RORCDGAT1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118355004-A | Cyclopropyl- (heteroaryl) -substituted ethylsulfonyl-pyridine derivatives | 勃林格殷格翰动物保健有限公司 | 2024-07-16 | — | — | CN | disclosed |