Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | GPR6 | P46095 | 4/20 | 0.39 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30989858 | 0.92 | GPR6 (0.39) | NTRK1GPR6P2RX7PDE4APDE4B | |
| SCHEMBL30989846 | 0.91 | GPR6 (0.42) | NTRK1GPR6P2RX7KCNH2SCN5A | |
| SCHEMBL30989834 | 0.88 | P2RX7 (0.37) | NTRK1P2RX7PDE4APDE4BPDE4D | |
| SCHEMBL30989892 | 0.81 | NTRK1 (0.46) | NTRK1GPR6P2RX7 | |
| SCHEMBL30989859 | 0.79 | GPR6 (0.39) | NTRK1GPR6 | |
| SCHEMBL30989838 | 0.79 | GPR6 (0.39) | NTRK1GPR6 | |
| SCHEMBL30990005 | 0.78 | MAPK1 (0.40) | GPR6MAP3K5P2RX7PDE4APDE4B | |
| SCHEMBL30989885 | 0.78 | MAPK1 (0.43) | P2RX7RIPK1 | |
| SCHEMBL31078468 | 0.77 | MAPT (0.44) | MEN1KMT2A | |
| SCHEMBL30989853 | 0.76 | PDE4A (0.54) | PDE4APDE4BPDE4DMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612131-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024095003-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2024-05-10 | — | — | WO | disclosed |