Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 11/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.37 |
| ▸ | KDM6B | O15054 | 3/20 | 0.37 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30989774 | 0.90 | GPR6 (0.37) | KDM4CGPBAR1GPR6PIK3C3OXTR | |
| SCHEMBL30989950 | 0.90 | GPR6 (0.37) | KDM4CGPBAR1GPR6PIK3C3OXTR | |
| SCHEMBL30990023 | 0.89 | MAPK1 (0.43) | KDM4CGPBAR1PIK3C3PTGDR2 | |
| SCHEMBL30989941 | 0.89 | MAPK1 (0.43) | KDM4CGPBAR1PIK3C3PTGDR2 | |
| SCHEMBL30989852 | 0.85 | GPBAR1 (0.36) | KDM4CGPBAR1GPR6PIK3C3ADRA2A | |
| SCHEMBL30989913 | 0.85 | GPBAR1 (0.36) | KDM4CGPBAR1GPR6PIK3C3ADRA2A | |
| SCHEMBL30989831 | 0.83 | MAPK1 (0.41) | KDM4CGPBAR1GPR6PIK3C3KDM6B | |
| SCHEMBL30990026 | 0.83 | MAPK1 (0.41) | KDM4CGPBAR1GPR6PIK3C3KDM6B | |
| SCHEMBL30989826 | 0.82 | GPR6 (0.39) | GPBAR1GPR6PIK3C3 | |
| SCHEMBL30989859 | 0.81 | GPR6 (0.39) | KDM4CGPBAR1GPR6PIK3C3NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612131-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024095003-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2024-05-10 | — | — | WO | disclosed |