Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 4/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | BUB1 | O43683 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30990201 | 1.00 | NR1H2 (0.41) | NR1H2GPR119ESR2SRD5A1HDAC1 | |
| SCHEMBL1003642 | 0.80 | NR1H2 (0.41) | NR1H2GPR119ESR2HDAC1UCHL1 | |
| SCHEMBL24374827 | 0.79 | GLA (0.39) | GPR119NPC1RAB9AKDM4E | |
| SCHEMBL29618505 | 0.79 | NPC1 (0.37) | NR1H2GPR119ESR2USP30NPC1 | |
| SCHEMBL7977206 | 0.72 | NR1H2 (0.55) | NR1H2HDAC1HDAC6KDM4E | |
| SCHEMBL30990279 | 0.71 | NR1H2 (0.37) | NR1H2GPR119ESR2HDAC1 | |
| SCHEMBL1004859 | 0.70 | NR1H2 (0.40) | NR1H2HDAC1UCHL1USP30ELANE | |
| SCHEMBL16115882 | 0.69 | NR1H2 (0.40) | NR1H2GPR119HDAC1UCHL1USP30 | |
| SCHEMBL18537881 | 0.68 | NR1H2 (0.53) | NR1H2 | |
| SCHEMBL30853473 | 0.68 | ALDH1A1 (0.49) | NR1H2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626860-A1 | FUSED PYRROLYL-SULFONAMIDE COMPOUNDS | ReWind Therapeutics NV (BE) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024115733-A1 | FUSED PYRROLYL-SULFONAMIDE COMPOUNDS | REWIND THERAPEUTICS NV (BE) | 2024-06-06 | — | — | WO | disclosed |