SCHEMBL30990246

SCHEMBL30990246

CCOC(=O)c1[nH]c2cc(Cl)sc2c1S(N)(=O)=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 7/20 0.43
▸ TUBB4A P04350 1/20 0.43
▸ TUBB P07437 1/20 0.43
▸ TUBA3C P0DPH7 1/20 0.43
▸ TUBA1B P68363 1/20 0.43
▸ TUBA4A P68366 1/20 0.43
▸ TUBB4B P68371 1/20 0.43
▸ TUBB3 Q13509 1/20 0.43
▸ TUBB2A Q13885 1/20 0.43
▸ TUBB8 Q3ZCM7 1/20 0.43
▸ TUBA3E Q6PEY2 1/20 0.43
▸ TUBA1A Q71U36 1/20 0.43
▸ TUBA1C Q9BQE3 1/20 0.43
▸ TUBB6 Q9BUF5 1/20 0.43
▸ TUBB2B Q9BVA1 1/20 0.43
▸ TUBB1 Q9H4B7 1/20 0.43
▸ ALDH1A1 P00352 5/20 0.42
▸ MAPT P10636 4/20 0.42
▸ GALR3 O60755 1/20 0.42
▸ LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30990311 0.90 ALOX15 (0.44) ALOX15TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL30990214 0.89 ALOX15 (0.44) ALOX15TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL30990290 0.73 LMNA (0.38) ALOX15TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL8478442 0.71 CA1 (0.53) ALOX15ALDH1A1MAPTLMNAKDM4E
SCHEMBL30990295 0.69 ALOX15 (0.44) ALOX15TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL1244756 0.68 ALOX15 (0.56) ALOX15ALDH1A1MAPTLMNAKDM4E
SCHEMBL23293695 0.66 KDM4E (0.45) ALOX15TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL15841317 0.66 KDM4E (0.45) ALOX15TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL6626737 0.66 ALOX15 (0.43) ALOX15ALDH1A1MAPTGALR3LMNA
SCHEMBL1710999 0.65 ALOX15 (0.53) ALOX15TUBB4ATUBBTUBA3CTUBA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626860-A1 FUSED PYRROLYL-SULFONAMIDE COMPOUNDS ReWind Therapeutics NV (BE) 2025-10-08 — — EP disclosed
WO-2024115733-A1 FUSED PYRROLYL-SULFONAMIDE COMPOUNDS REWIND THERAPEUTICS NV (BE) 2024-06-06 — — WO disclosed
Send feedback