SCHEMBL30990404

SCHEMBL30990404

CCCc1nc(C(F)(F)F)ccc1C=CC(=O)N[C@H](C)c1cc(F)c(NS(C)(=O)=O)c(F)c1

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 19/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3777464 1.00 TRPV1 (0.50) TRPV1
SCHEMBL13018232 1.00 TRPV1 (0.50) TRPV1
SCHEMBL3777469 1.00 TRPV1 (0.50) TRPV1
SCHEMBL3777466 1.00 TRPV1 (0.50) TRPV1
SCHEMBL29379519 1.00 TRPV1 (0.50) TRPV1
SCHEMBL4563844 1.00 TRPV1 (0.50) TRPV1
SCHEMBL3782166 0.95 TRPV1 (0.49) TRPV1
SCHEMBL3782163 0.95 TRPV1 (0.49) TRPV1
SCHEMBL3782164 0.95 TRPV1 (0.49) TRPV1
SCHEMBL4434439 0.95 TRPV1 (0.49) TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112996489-B Sol-gel composition 株式会社爱茉莉太平洋 2024-08-02 CN claimed
EP-3666254-B1 PHARMACEUTICAL COMPOSITION CONTAINING (R)-N-[1-(3,5-DIFLUORO-4-METHANSULFONYLAMINO-PHENYL)-ETHYL]-3-(2-PROPYL-6-TRIFLUOROMETHYL-PYRIDIN-3-YL)-ACRYLAMIDE AMOREPACIFIC CORP (KR) 2024-12-04 EP disclosed
EP-3666254-C0 PHARMACEUTICAL COMPOSITION CONTAINING (R)-N-[1-(3,5-DIFLUORO-4-METHANSULFONYLAMINO-PHENYL)-ETHYL]-3-(2-PROPYL-6-TRIFLUOROMETHYL-PYRIDIN-3-YL)-ACRYLAMIDE AMOREPACIFIC CORP (KR) 2024-12-04 EP disclosed
US-12059412-B2 Pharmaceutical composition containing (R)-N-[1-(3,5-difluoro-4-methanesulfonylamino-phenyl)-ethyl]-3-(2-propyl-6-trifluoromethylpyridin-3-yl)-acrylamide and method for inhibiting crystal formation thereof AMOREPACIFIC CORPORATION (KR) 2024-08-13 US disclosed
CN-112996489-B Sol-gel composition 株式会社爱茉莉太平洋 2024-08-02 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12059412-B2 Pharmaceutical composition containing (R)-N-[1-(3,5-difluoro-4-methanesulfonylamino-phenyl)-ethyl]-3-(2-propyl-6-trifluoromethylpyridin-3-yl)-acrylamide and method for inhibiting crystal formation thereof SULT2A1, SULT1E1, SULT1A1 TRPV1 2202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.