Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALPL | P05186 | 4/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SGK1 | O00141 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23620131 | 1.00 | MEN1 (0.53) | MEN1KMT2APABPC1HTTTSHR | |
| SCHEMBL23620235 | 0.85 | EDNRA (0.45) | MEN1KMT2AALDH1A1ALPLSGK1 | |
| SCHEMBL30991306 | 0.85 | EDNRA (0.46) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL23620224 | 0.85 | EDNRA (0.46) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL21596682 | 0.83 | SGK1 (0.40) | MEN1KMT2AALDH1A1ALPLSGK1 | |
| SCHEMBL29363179 | 0.83 | SGK1 (0.40) | MEN1KMT2AALDH1A1ALPLSGK1 | |
| SCHEMBL21545957 | 0.81 | CES1 (0.47) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL29561166 | 0.81 | CES1 (0.47) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL23620236 | 0.80 | SGK1 (0.43) | ALDH1A1ALPLSGK1 | |
| SCHEMBL23620165 | 0.80 | NR4A2 (0.42) | MEN1KMT2ATSHRALDH1A1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469710-B | Pyridyl and pyrazinyl- (aza) indole sulfonamides | 优时比制药有限公司 | 2024-05-14 | — | — | CN | disclosed |