Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | SGK1 | O00141 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 4/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23620224 | 1.00 | EDNRA (0.46) | EDNRASGK1ALDH1A1ALPLPPARG | |
| SCHEMBL21596682 | 0.88 | SGK1 (0.40) | SGK1ALDH1A1ALPLPPARGMEN1 | |
| SCHEMBL29363179 | 0.88 | SGK1 (0.40) | SGK1ALDH1A1ALPLPPARGMEN1 | |
| SCHEMBL23620235 | 0.88 | EDNRA (0.45) | EDNRASGK1ALDH1A1ALPLPPARG | |
| SCHEMBL21545957 | 0.86 | CES1 (0.47) | EDNRASGK1ALDH1A1MEN1KMT2A | |
| SCHEMBL29561166 | 0.86 | CES1 (0.47) | EDNRASGK1ALDH1A1MEN1KMT2A | |
| SCHEMBL23620236 | 0.85 | SGK1 (0.43) | SGK1ALDH1A1ALPLPPARG | |
| SCHEMBL23620131 | 0.85 | MEN1 (0.53) | SGK1ALDH1A1ALPLMEN1KMT2A | |
| SCHEMBL30991273 | 0.85 | MEN1 (0.53) | SGK1ALDH1A1ALPLMEN1KMT2A | |
| SCHEMBL30991296 | 0.85 | SGK1 (0.43) | SGK1ALDH1A1ALPLPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469710-B | Pyridyl and pyrazinyl- (aza) indole sulfonamides | 优时比制药有限公司 | 2024-05-14 | — | — | CN | disclosed |