Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGK1 | O00141 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29363179 | 1.00 | SGK1 (0.40) | SGK1ALDH1A1DYRK1AALPLPPARG | |
| SCHEMBL30991306 | 0.88 | EDNRA (0.46) | SGK1ALDH1A1DYRK1AALPLPPARG | |
| SCHEMBL23620224 | 0.88 | EDNRA (0.46) | SGK1ALDH1A1DYRK1AALPLPPARG | |
| SCHEMBL23620235 | 0.86 | EDNRA (0.45) | SGK1ALDH1A1DYRK1AALPLPPARG | |
| SCHEMBL21545957 | 0.84 | CES1 (0.47) | SGK1ALDH1A1MEN1KMT2A | |
| SCHEMBL29561166 | 0.84 | CES1 (0.47) | SGK1ALDH1A1MEN1KMT2A | |
| SCHEMBL23620236 | 0.83 | SGK1 (0.43) | SGK1ALDH1A1ALPLPPARG | |
| SCHEMBL23620131 | 0.83 | MEN1 (0.53) | SGK1ALDH1A1ALPLMEN1KMT2A | |
| SCHEMBL30991296 | 0.83 | SGK1 (0.43) | SGK1ALDH1A1ALPLPPARG | |
| SCHEMBL30991273 | 0.83 | MEN1 (0.53) | SGK1ALDH1A1ALPLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469710-B | Pyridyl and pyrazinyl- (aza) indole sulfonamides | 优时比制药有限公司 | 2024-05-14 | — | — | CN | claimed |
| US-11939319-B2 | Pyridinyl and pyrazinyl-(asa)indolsulfonamides | UCB PHARMA GMBH (DE) | 2024-03-26 | — | — | US | claimed |
| EP-3810591-B1 | PYRIDINYL AND PYRAZINYL-(AZA)INDOLSULFONAMIDES | UCB PHARMA GMBH (DE) | 2022-08-10 | — | — | EP | claimed |
| US-20210206749-A1 | Pyridinyl and Pyrazinyl-(Asa)Indolsulfonamides | UCB PHARMA GMBH (DE) | 2021-07-08 | — | — | US | claimed |
| EP-3810591-A1 | PYRIDINYL AND PYRAZINYL-(AZA)INDOLSULFONAMIDES | UCB Pharma GmbH (DE) | 2021-04-28 | — | — | EP | claimed |
| CN-112469710-A | Pyridyl and pyrazinyl- (aza) indole sulfonamides | 优时比制药有限公司 | 2021-03-09 | — | — | CN | claimed |
| WO-2019243303-A1 | PYRIDINYL AND PYRAZINYL-(AZA)INDOLSULFONAMIDES | UCB PHARMA GMBH (DE) | 2019-12-26 | — | — | WO | claimed |
| US-12358875-B2 | N-(phenyl)-indole-3-sulfonamide derivatives and related compounds as GPR17 modulators for treating CNS disorders such as multiple sclerosis | UCB PHARMA GMBH (DE) | 2025-07-15 | — | — | US | disclosed |
| CN-112469710-B | Pyridyl and pyrazinyl- (aza) indole sulfonamides | 优时比制药有限公司 | 2024-05-14 | — | — | CN | disclosed |
| US-11939319-B2 | Pyridinyl and pyrazinyl-(asa)indolsulfonamides | UCB PHARMA GMBH (DE) | 2024-03-26 | — | — | US | disclosed |
| US-11939319-B2 | Pyridinyl and pyrazinyl-(asa)indolsulfonamides | UCB PHARMA GMBH (DE) | 2024-03-26 | — | — | US | disclosed |
| US-11939319-B2 | Pyridinyl and pyrazinyl-(asa)indolsulfonamides | UCB PHARMA GMBH (DE) | 2024-03-26 | — | — | US | disclosed |
| EP-4074703-B1 | PYRIDINYL-(AZA)INDOLSULFONAMIDES | UCB PHARMA GMBH (DE) | 2023-11-29 | — | — | EP | disclosed |
| CN-113993845-A | N- (phenyl) -indole-3-sulfonamide derivatives and related compounds as GPR17 modulators for the treatment of CNS disorders, such as multiple sclerosis | 优时比制药有限公司 | 2022-01-28 | — | — | CN | disclosed |
| US-20210206749-A1 | Pyridinyl and Pyrazinyl-(Asa)Indolsulfonamides | UCB PHARMA GMBH (DE) | 2021-07-08 | — | — | US | disclosed |
| US-20210206749-A1 | Pyridinyl and Pyrazinyl-(Asa)Indolsulfonamides | UCB PHARMA GMBH (DE) | 2021-07-08 | — | — | US | disclosed |
| EP-3810591-A1 | PYRIDINYL AND PYRAZINYL-(AZA)INDOLSULFONAMIDES | UCB Pharma GmbH (DE) | 2021-04-28 | — | — | EP | disclosed |
| CN-112469710-A | Pyridyl and pyrazinyl- (aza) indole sulfonamides | 优时比制药有限公司 | 2021-03-09 | — | — | CN | disclosed |
| WO-2020254289-A1 | N-(PHENYL)-INDOLE-3-SULFONAMIDE DERIVATIVES AND RELATED COMPOUNDS AS GPR17 MODULATORS FOR TREATING CNS DISORDERS SUCH AS MULTIPLE SCLEROSIS | UCB PHARMA GMBH (DE) | 2020-12-24 | — | — | WO | disclosed |
| WO-2019243303-A1 | PYRIDINYL AND PYRAZINYL-(AZA)INDOLSULFONAMIDES | UCB PHARMA GMBH (DE) | 2019-12-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12358875-B2 | N-(phenyl)-indole-3-sulfonamide derivatives and related compounds as GPR17 modulators for treating CNS disorders such as multiple sclerosis | GPR27, GPR18, GPR17 | SGK1 3128/4885ALDH1A1 2081/4885DYRK1A 2831/4885 |
| US-20210206749-A1 | Pyridinyl and Pyrazinyl-(Asa)Indolsulfonamides | GPR17, GPR18, GPR119 | SGK1 1683/4885ALDH1A1 732/4885DYRK1A 3097/4885 |
| US-11939319-B2 | Pyridinyl and pyrazinyl-(asa)indolsulfonamides | GPR17, GPR18, GPR119 | SGK1 1683/4885ALDH1A1 732/4885DYRK1A 3097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.