Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 3/20 | 0.45 |
| ▸ | CCR4 | P51679 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23620132 | 1.00 | EDNRA (0.45) | EDNRACCR4DYRK1ANR4A2GPR84 | |
| SCHEMBL20339142 | 0.85 | POLB (0.50) | EDNRAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL23620235 | 0.84 | EDNRA (0.45) | EDNRACCR4DYRK1AMEN1KMT2A | |
| SCHEMBL30286552 | 0.81 | EDNRA (0.45) | EDNRADYRK1ANR4A2GPR84POLB | |
| SCHEMBL20355221 | 0.81 | KMT2A (0.48) | EDNRAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL20354701 | 0.81 | SLC22A12 (0.47) | HTT | |
| SCHEMBL20355218 | 0.81 | EDNRA (0.45) | EDNRADYRK1ANR4A2GPR84POLB | |
| SCHEMBL29560013 | 0.81 | SLC22A12 (0.47) | HTT | |
| SCHEMBL20339162 | 0.79 | NR4A2 (0.36) | EDNRADYRK1ANR4A2GPR84POLB | |
| SCHEMBL30286553 | 0.79 | NR4A2 (0.36) | EDNRADYRK1ANR4A2GPR84POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469710-B | Pyridyl and pyrazinyl- (aza) indole sulfonamides | 优时比制药有限公司 | 2024-05-14 | — | — | CN | disclosed |