Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3103587 | 0.86 | TSHR (0.34) | PPARDTSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3109175 | 0.76 | TSHR (0.39) | PPARDTSHRPLAUCYP3A4CYP2C9 | |
| SCHEMBL3094150 | 0.75 | PLAU (0.36) | PPARDTSHRPLAU | |
| SCHEMBL3097313 | 0.73 | TSHR (0.36) | PPARDTSHRPLAUCYP3A4CYP2C9 | |
| SCHEMBL3103505 | 0.73 | PPARD (0.40) | PPARDTSHRPLAUCYP3A4CYP2C9 | |
| SCHEMBL3091598 | 0.73 | PLAU (0.34) | PPARDTSHRPLAU | |
| SCHEMBL3097947 | 0.72 | TSHR (0.35) | PPARDTSHRPLAU | |
| SCHEMBL3100652 | 0.72 | TSHR (0.35) | PPARDTSHRPLAU | |
| SCHEMBL3098098 | 0.72 | FPR2 (0.43) | PPARDTSHRPLAU | |
| SCHEMBL3097963 | 0.71 | TSHR (0.34) | PPARDTSHRPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |