SCHEMBL3097313

SCHEMBL3097313

CCOP(=O)(CN[C@H](C(N)=O)C(C)C)OCC

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
PPARD Q03181 1/20 0.36
ALDH1A1 P00352 1/20 0.35
FPR2 P25090 5/20 0.35
PLAU P00749 1/20 0.34
CA12 O43570 2/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
GAA P10253 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
HTT P42858 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3100652 0.89 TSHR (0.35) TSHRPPARDFPR2PLAUCA12
SCHEMBL3102486 0.87 FPR2 (0.44) TSHRPPARDALDH1A1FPR2PLAU
SCHEMBL3097993 0.85 ALDH1A1 (0.46) TSHRPPARDALDH1A1FPR2CA12
SCHEMBL3109175 0.83 TSHR (0.39) TSHRPPARDALDH1A1FPR2PLAU
SCHEMBL3103058 0.78 FPR2 (0.44) TSHRPPARDFPR2PLAUCA12
SCHEMBL3100531 0.77 LAP3 (0.37) ALDH1A1
SCHEMBL3100524 0.77 LAP3 (0.37) ALDH1A1
SCHEMBL3103505 0.77 PPARD (0.40) TSHRPPARDFPR2PLAUCA12
SCHEMBL3098905 0.77 FPR2 (0.45) TSHRPPARDALDH1A1FPR2CA1
SCHEMBL3095559 0.77 ALDH1A1 (0.38) TSHRPPARDALDH1A1FPR2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100247463-A1 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE YU RUEY J 2010-09-30 US claimed