Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 4/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30992283 | 0.90 | CCNB2 (0.36) | IMPDH2CCNB2CDK1CCNB1GSK3B | |
| SCHEMBL30992285 | 0.87 | IMPDH2 (0.41) | IMPDH2PTPN1BRD4NR1H2NR1H3 | |
| SCHEMBL30992253 | 0.86 | IMPDH2 (0.39) | IMPDH2PTPN1NR1H2NR1H3RXRA | |
| SCHEMBL24446810 | 0.80 | IMPDH2 (0.40) | IMPDH2PTPN1CCNB2CDK1CCNB1 | |
| SCHEMBL30992237 | 0.80 | IMPDH2 (0.40) | IMPDH2PTPN1BRD4NR1H2NR1H3 | |
| SCHEMBL30992254 | 0.78 | IMPDH2 (0.39) | IMPDH2PTPN1NR1H2NR1H3 | |
| SCHEMBL30992248 | 0.78 | IMPDH2 (0.43) | IMPDH2PTPN1NR1H2NR1H3RXRA | |
| SCHEMBL22300223 | 0.77 | IDO1 (0.40) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL30890749 | 0.77 | NR1H2 (0.42) | BRD4NR1H2NR1H3RXRA | |
| SCHEMBL30890471 | 0.77 | NR1H2 (0.41) | NR1H2NR1H3RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199647-A1 | ANTI-VIRAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199647-A1 | ANTI-VIRAL COMPOUNDS | EIF2AK2, ZC3HAV1, HAVCR2 | IMPDH2 1033/4885PTPN1 1570/4885CCNB2 3759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.