Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 3/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.35 |
| ▸ | RXRA | P19793 | 4/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 3/20 | 0.34 |
| ▸ | CDK2 | P24941 | 3/20 | 0.34 |
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.32 |
| ▸ | TTK | P33981 | 2/20 | 0.32 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30890440 | 0.91 | NR1H2 (0.35) | IMPDH2NR1H2NR1H3RXRAAURKA | |
| SCHEMBL30992255 | 0.86 | IMPDH2 (0.40) | IMPDH2NR1H2NR1H3RXRAPTPN1 | |
| SCHEMBL30992285 | 0.84 | IMPDH2 (0.41) | IMPDH2NR1H2NR1H3RXRAPTPN1 | |
| SCHEMBL25756973 | 0.82 | IP6K1 (0.42) | IMPDH2NR1H2NR1H3RXRAPTPN1 | |
| SCHEMBL27245195 | 0.79 | OTUD7B (0.37) | OTUD7BIP6K1 | |
| SCHEMBL27245173 | 0.78 | OTUD7B (0.36) | OTUD7BIP6K1 | |
| SCHEMBL30992237 | 0.77 | IMPDH2 (0.40) | IMPDH2NR1H2NR1H3RXRAPTPN1 | |
| SCHEMBL30992283 | 0.76 | CCNB2 (0.36) | IMPDH2NR1H2NR1H3RXRA | |
| SCHEMBL30992254 | 0.76 | IMPDH2 (0.39) | IMPDH2NR1H2NR1H3PTPN1 | |
| SCHEMBL30992248 | 0.75 | IMPDH2 (0.43) | IMPDH2NR1H2NR1H3RXRAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199647-A1 | ANTI-VIRAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199647-A1 | ANTI-VIRAL COMPOUNDS | EIF2AK2, ZC3HAV1, HAVCR2 | IMPDH2 1033/4885NR1H2 449/4885NR1H3 380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.