Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | GRM1 | Q13255 | 7/20 | 0.46 |
| ▸ | GRM5 | P41594 | 7/20 | 0.46 |
| ▸ | WNT3A | P56704 | 1/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.45 |
| ▸ | LIPC | P11150 | 1/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | CDK7 | P50613 | 1/20 | 0.44 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30074970 | 0.92 | CNR1 (0.55) | CNR1NAMPTGRM1GRM5WNT3A | |
| SCHEMBL1199869 | 0.85 | NAMPT (0.53) | CNR1NAMPTGRM1GRM5WNT3A | |
| SCHEMBL31336142 | 0.83 | GRM5 (0.51) | CNR1NAMPTGRM1GRM5WNT3A | |
| SCHEMBL8512618 | 0.83 | GRM5 (0.51) | CNR1NAMPTGRM1GRM5WNT3A | |
| SCHEMBL25130586 | 0.83 | CNR1 (0.52) | CNR1GRM1GRM5CCNT1CDK9 | |
| SCHEMBL1868160 | 0.82 | NAMPT (0.48) | CNR1NAMPTGRM1GRM5WNT3A | |
| SCHEMBL19701850 | 0.82 | NAMPT (0.54) | CNR1NAMPTGRM1GRM5WNT3A | |
| SCHEMBL3195957 | 0.82 | NAMPT (0.56) | CNR1NAMPTGRM1GRM5PDK4 | |
| SCHEMBL19703157 | 0.81 | NAMPT (0.53) | CNR1NAMPTGRM1GRM5CDK9 | |
| SCHEMBL14857260 | 0.81 | NAMPT (0.55) | CNR1NAMPTGRM1GRM5SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-20 | — | — | WO | disclosed |