Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 5/20 | 0.46 |
| ▸ | GRM5 | P41594 | 5/20 | 0.46 |
| ▸ | CDK7 | P50613 | 1/20 | 0.46 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.46 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.46 |
| ▸ | WNT3A | P56704 | 1/20 | 0.46 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7097586 | 0.90 | TNK2 (0.48) | NAMPTCNR1GRM1GRM5CDK7 | |
| SCHEMBL30074970 | 0.84 | CNR1 (0.55) | NAMPTCNR1GRM1GRM5CDK7 | |
| Trifluoroacetic Acid SCHEMBL1873263 | 0.83 | TNK2 (0.51) | NAMPTGRM1GRM5CDK7CDK13 | |
| SCHEMBL8512618 | 0.83 | GRM5 (0.51) | NAMPTCNR1GRM1GRM5WNT3A | |
| SCHEMBL31336142 | 0.83 | GRM5 (0.51) | NAMPTCNR1GRM1GRM5WNT3A | |
| SCHEMBL30993158 | 0.82 | CNR1 (0.51) | NAMPTCNR1GRM1GRM5CDK7 | |
| SCHEMBL25457026 | 0.80 | CNR1 (0.49) | CNR1GRM1GRM5TNK2CCNT1 | |
| SCHEMBL31227073 | 0.80 | WNT3A (0.61) | NAMPTGRM1GRM5WNT3ATNK2 | |
| SCHEMBL171730 | 0.80 | WNT3A (0.61) | NAMPTGRM1GRM5WNT3ATNK2 | |
| SCHEMBL24165469 | 0.80 | NAMPT (0.50) | NAMPTCNR1GRM1GRM5CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7947684-B2 | anticoagulants; immunomoderators; antiinflammatory agents | AVENTIS PHARMACEUTICALS INC. (US) | 2011-05-24 | — | — | US | disclosed |
| US-20040220171-A1 | 1-Aroyl-piperidinyl benzamidines | AVENTIS PHARMACEUTICALS INC | 2004-11-04 | — | — | US | disclosed |
| US-20020045613-A1 | 1-aroyl-piperidinyl benzamidines | AVENTIS PHARMACEUTICALS PRODUCTS INC. | 2002-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220171-A1 | 1-Aroyl-piperidinyl benzamidines | TPSAB1, TPSB2, CMA1 | NAMPT 596/4885CNR1 449/4885GRM1 2239/4885 |
| US-20020045613-A1 | 1-aroyl-piperidinyl benzamidines | TPSAB1, TPSB2, CMA1 | NAMPT 596/4885CNR1 449/4885GRM1 2239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.