SCHEMBL30993227

SCHEMBL30993227

Cn1c(=O)n(C)c2c(I)cc(Br)cc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.47
MAOB P27338 2/20 0.43
MAOA P21397 1/20 0.43
ATAD2 Q6PL18 1/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ATM Q13315 1/20 0.37
IDO1 P14902 1/20 0.35
BRPF1 P55201 3/20 0.35
BRD1 O95696 2/20 0.35
TAF1 P21675 2/20 0.35
ADORA2B P29275 2/20 0.34
PIK3CD O00329 1/20 0.33
PIK3CA P42336 1/20 0.33
PIK3CB P42338 1/20 0.33
PIK3CG P48736 1/20 0.33
ADORA2A P29274 1/20 0.33
S100B P04271 1/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4621797 0.81 HSD17B10 (0.50) HSD17B10MAOBMAOAATAD2MEN1
SCHEMBL31393662 0.79 HSD17B10 (0.49) HSD17B10MAOBMAOAATAD2MEN1
SCHEMBL30992982 0.78 ATAD2 (0.52) HSD17B10MAOBMAOAATAD2MEN1
SCHEMBL29704633 0.78 HSD17B10 (0.47) HSD17B10MAOBMAOAATAD2MEN1
SCHEMBL17421014 0.78 HSD17B10 (0.47) HSD17B10MAOBMAOAATAD2MEN1
SCHEMBL20983203 0.78 HSD17B10 (0.47) HSD17B10MAOBMAOAATAD2MEN1
SCHEMBL30993461 0.76 HSD17B10 (0.46) HSD17B10MAOBMAOAATAD2MEN1
SCHEMBL30993044 0.75 HSD17B10 (0.45) HSD17B10MAOBMAOAATAD2MEN1
SCHEMBL31248608 0.74 HSD17B10 (0.44) HSD17B10MAOBMAOAATAD2MEN1
SCHEMBL30993758 0.73 MAPT (0.46) HSD17B10MAOBMAOAATAD2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720057-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) 2026-04-08 EP disclosed
US-20250136578-A1 BIFUNCTIONAL ANDROGEN RECEPTOR COMPOUNDS KOLM THERAPEUTICS INC. 2025-05-01 US disclosed
US-20250129070-A1 BIFUNCTIONAL ANDROGEN RECEPTOR COMPOUNDS KOLM THERAPEUTICS INC. 2025-04-24 US disclosed
WO-2025081092-A1 BIFUNCTIONAL ANDROGEN RECEPTOR COMPOUNDS KOLM THERAPEUTICS INC. (US) 2025-04-17 WO disclosed
WO-2025081082-A1 BIFUNCTIONAL ANDROGEN RECEPTOR COMPOUNDS KOLM THERAPEUTICS INC. (US) 2025-04-17 WO disclosed
WO-2025049976-A1 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2025-03-06 WO disclosed
WO-2024249888-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2024-12-05 WO disclosed
WO-2024130095-A1 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250136578-A1 BIFUNCTIONAL ANDROGEN RECEPTOR COMPOUNDS AR, SHBG, FSHR HSD17B10 299/4885MAOB 3455/4885MAOA 3073/4885
US-20250129070-A1 BIFUNCTIONAL ANDROGEN RECEPTOR COMPOUNDS AR, SHBG, FSHR HSD17B10 299/4885MAOB 3455/4885MAOA 3073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.