Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDE | P14735 | 2/20 | 0.51 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | SUV39H2 | Q9H5I1 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CCNK | O75909 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28578728 | 0.91 | MAPT (0.49) | IDEMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL30074969 | 0.91 | MAPT (0.49) | IDEMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL30993258 | 0.87 | MAPT (0.49) | IDEMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL20768985 | 0.84 | SMYD3 (0.70) | IDESMYD3MEN1KMT2AMAPT | |
| SCHEMBL1432796 | 0.81 | POLB (0.53) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL3709053 | 0.81 | IDE (0.76) | IDEMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10058374 | 0.80 | MAP4K4 (0.61) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL30992952 | 0.80 | MAPT (0.51) | MAPTALDH1A1LMNASMN1; SMN2ALK | |
| SCHEMBL2420167 | 0.80 | POLB (0.52) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL30208188 | 0.80 | MAPT (0.72) | MEN1KMT2AMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A9 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-08-02 | — | — | WO | disclosed |
| WO-2024130095-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-20 | — | — | WO | disclosed |