Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | IDE | P14735 | 2/20 | 0.46 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30993299 | 0.87 | IDE (0.51) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL30074969 | 0.80 | MAPT (0.49) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL28578728 | 0.80 | MAPT (0.49) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL10058374 | 0.80 | MAP4K4 (0.61) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2420167 | 0.80 | POLB (0.52) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL31146989 | 0.79 | LMNA (0.48) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL3768455 | 0.78 | PRKDC (0.57) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL10320809 | 0.77 | WNT3A (0.56) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL194454 | 0.77 | MAPT (0.53) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2419663 | 0.77 | POLB (0.52) | MAPTALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A9 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-08-02 | — | — | WO | disclosed |
| WO-2024130095-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-20 | — | — | WO | disclosed |