⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20438536 | 0.64 | MPO (0.38) | — | |
| SCHEMBL4506135 | 0.63 | PIN1 (0.46) | — | |
| SCHEMBL31022920 | 0.63 | HTT (0.36) | — | |
| SCHEMBL21453678 | 0.63 | — | — | |
| SCHEMBL21435034 | 0.63 | MAP4K1 (0.32) | — | |
| SCHEMBL8493175 | 0.63 | — | — | |
| SCHEMBL21435100 | 0.62 | — | — | |
| SCHEMBL21435069 | 0.62 | — | — | |
| SCHEMBL12775584 | 0.61 | TSHR (0.35) | — | |
| SCHEMBL23670668 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-20 | — | — | WO | disclosed |