SCHEMBL3099376

SCHEMBL3099376

C=C(CCCCC(=O)O)C(=C)C(=C)C(=C)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
TSHR P16473 5/20 0.48
NFKB1 P19838 2/20 0.48
PMP22 Q01453 1/20 0.48
SLC22A6 Q4U2R8 2/20 0.43
GPR84 Q9NQS5 5/20 0.41
FFAR1 O14842 2/20 0.41
FFAR4 Q5NUL3 2/20 0.41
AKR1B1 P15121 1/20 0.41
CYP2D6 P10635 1/20 0.41
FOLH1 Q04609 1/20 0.41
ABCC4 O15439 1/20 0.40
MAPT P10636 1/20 0.40
PPARG P37231 6/20 0.39
PPARD Q03181 6/20 0.39
PPARA Q07869 6/20 0.39
HDAC11 Q96DB2 5/20 0.39
ALDH1A1 P00352 2/20 0.39
TLR2 O60603 2/20 0.39
TDP1 Q9NUW8 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8981889 1.00 LMNA (0.50) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL28333158 0.98 TSHR (0.52) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL5447811 0.88 TSHR (0.57) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL28267218 0.88 TSHR (0.57) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL6440084 0.86 LMNA (0.45) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL9437313 0.86 LMNA (0.45) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL7153146 0.86 LMNA (0.45) LMNATSHRNFKB1PMP22SLC22A6
Ammonia Solution, Strong SCHEMBL28483916 0.84 EGLN1 (0.43) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL11061405 0.83 LMNA (0.47) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL1264711 0.83 AKR1B1 (0.48) TSHRSLC22A6GPR84FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1058703-B1 A METHOD FOR INCREASING THE MOLECULAR WEIGHT OF POLYESTER RESINS MINI RICERCA SCIENT TECNOLOG (IT) 2003-10-15 EP claimed
US-6388025-B1 Method for increasing the molecular weight of polyester resins MINISTERO DELL'UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) 2002-05-14 US claimed
US-8415270-B2 Heat sensitive recording material comprising a protective layer KANZAKI SPECIALTY PAPERS (US) 2013-04-09 US disclosed
US-20100190644-A1 HEAT SENSITIVE RECORDING MATERIAL COMPRISING A PROTECTIVE LAYER KANZAKI SPECIALTY PAPERS 2010-07-29 US disclosed
US-6388025-B1 Method for increasing the molecular weight of polyester resins MINISTERO DELL'UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) 2002-05-14 US disclosed
EP-1058703-A1 A METHOD FOR INCREASING THE MOLECULAR WEIGHT OF POLYESTER RESINS MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) 2000-12-13 EP disclosed
WO-1999028367-A1 A METHOD FOR INCREASING THE MOLECULAR WEIGHT OF POLYESTER RESINS MINISTERO DELL'UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) 1999-06-10 WO disclosed
US-4430131-A Polyurethane binders HER MAJESTY THE QUEEN IN RIGHT OF CANADA (CA) 1984-02-07 US disclosed
US-4415728-A BINDERS FOR SOLID PROPELLANTS HER MAJESTY THE QUEEN IN RIGHT OF CANADA (CA) 1983-11-15 US disclosed