Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.45 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.45 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.42 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.42 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | KDM5C | P41229 | 3/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM6B | O15054 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7153146 | 1.00 | LMNA (0.45) | LMNAEGLN1ALKBH5SUCNR1MAPK1 | |
| SCHEMBL6440084 | 1.00 | LMNA (0.45) | LMNAEGLN1ALKBH5SUCNR1MAPK1 | |
| Ammonia Solution, Strong SCHEMBL28483916 | 0.98 | EGLN1 (0.43) | LMNAEGLN1ALKBH5SUCNR1MAPK1 | |
| SCHEMBL11061405 | 0.97 | LMNA (0.47) | LMNAEGLN1ALKBH5SUCNR1MAPK1 | |
| SCHEMBL3099376 | 0.86 | LMNA (0.50) | LMNAOR51E2SLC22A6TSHRHSD17B10 | |
| SCHEMBL8981889 | 0.86 | LMNA (0.50) | LMNAOR51E2SLC22A6TSHRHSD17B10 | |
| SCHEMBL28333158 | 0.84 | TSHR (0.52) | LMNAOR51E2SLC22A6TSHRHSD17B10 | |
| SCHEMBL6921772 | 0.81 | LMNA (0.41) | LMNAEGLN1ALKBH5SUCNR1MAPK1 | |
| SCHEMBL26631 | 0.78 | LMNA (0.56) | LMNAEGLN1ALKBH5SUCNR1MAPK1 | |
| SCHEMBL10663570 | 0.78 | LMNA (0.56) | LMNAEGLN1ALKBH5SUCNR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286825-A | Copolymer of tetrafluoroethylene and bis-2,2-trifluoromethyl-4,5-difluorodivinyl-1,3-dioxolanes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-02-15 | — | — | US | disclosed |
| US-5233058-A | Fluoro-2,2-dimethyldioxolanes; copolymers with tetrafluoroethylene | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-08-03 | — | — | US | disclosed |
| EP-0504322-A1 | PARTIALLY FLUORINATED COMPOUNDS AND POLYMERS. | DU PONT (US) | 1992-09-23 | — | — | EP | disclosed |
| WO-1991009025-A2 | PARTIALLY FLUORINATED COMPOUNDS AND POLYMERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-06-27 | — | — | WO | disclosed |