Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 5/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | ABL2 | P42684 | 2/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30994032 | 0.82 | SRC (0.42) | HCAR1JAK2JAK1SRCEGFR | |
| SCHEMBL31637295 | 0.82 | FEN1 (0.43) | HCAR1JAK2JAK1BRD4FNTA | |
| SCHEMBL30994180 | 0.81 | SRC (0.43) | HCAR1JAK2JAK1SRCEGFR | |
| SCHEMBL31265017 | 0.81 | HCAR1 (0.44) | HCAR1JAK2JAK1SRCEGFR | |
| SCHEMBL30994012 | 0.81 | SRC (0.41) | HCAR1JAK2JAK1SRCEGFR | |
| SCHEMBL30994150 | 0.80 | SRC (0.41) | HCAR1JAK2JAK1SRCEGFR | |
| SCHEMBL30994439 | 0.80 | SRC (0.42) | HCAR1JAK2JAK1SRCEGFR | |
| SCHEMBL30994103 | 0.78 | MEN1 (0.43) | HCAR1JAK2JAK1SRCEGFR | |
| SCHEMBL17144495 | 0.78 | HCAR1 (0.45) | HCAR1JAK2JAK1SRCEGFR | |
| SCHEMBL17143824 | 0.78 | HCAR1 (0.45) | HCAR1JAK2JAK1SRCEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4656635-A1 | SUBSTITUTED BENZENE COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2025-12-03 | — | — | EP | disclosed |
| WO-2024157953-A1 | SUBSTITUTED BENZENE COMPOUND | 第一三共株式会社 | 2024-08-02 | — | — | WO | disclosed |