Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 5/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | ABL2 | P42684 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CCND2 | P30279 | 1/20 | 0.37 |
| ▸ | CCND3 | P30281 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30994180 | 0.90 | SRC (0.43) | SRCEGFRABL1ABL2JAK2 | |
| SCHEMBL30994150 | 0.89 | SRC (0.41) | SRCEGFRABL1ABL2JAK2 | |
| SCHEMBL30994439 | 0.89 | SRC (0.42) | SRCEGFRABL1ABL2JAK2 | |
| SCHEMBL30994221 | 0.87 | JAK2 (0.40) | SRCEGFRABL1ABL2JAK2 | |
| SCHEMBL30994103 | 0.87 | MEN1 (0.43) | SRCEGFRABL1ABL2JAK2 | |
| SCHEMBL30994032 | 0.81 | SRC (0.42) | SRCEGFRABL1ABL2JAK2 | |
| SCHEMBL30994255 | 0.81 | HCAR1 (0.49) | SRCEGFRABL1ABL2JAK2 | |
| SCHEMBL30994390 | 0.80 | JAK2 (0.40) | JAK2JAK1HCAR1MEN1KMT2A | |
| SCHEMBL31006630 | 0.79 | NR3C1 (0.41) | SRCEGFRJAK2JAK1FPR2 | |
| SCHEMBL19731467 | 0.78 | SRC (0.54) | SRCEGFRABL1ABL2HCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4656635-A1 | SUBSTITUTED BENZENE COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2025-12-03 | — | — | EP | disclosed |
| WO-2024157953-A1 | SUBSTITUTED BENZENE COMPOUND | 第一三共株式会社 | 2024-08-02 | — | — | WO | disclosed |