Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26316395 | 1.00 | ACHE (0.39) | ACHEENPP2PTPN1L3MBTL1MAPT | |
| SCHEMBL2703903 | 0.86 | ACHE (0.39) | ACHEPTPN1L3MBTL1MAPTHPGD | |
| SCHEMBL29951021 | 0.86 | ACHE (0.39) | ACHEPTPN1L3MBTL1MAPTHPGD | |
| SCHEMBL772019 | 0.82 | ENPP2 (0.37) | ENPP2PTPN1MAPTTSHRALDH1A1 | |
| SCHEMBL2140990 | 0.81 | MAPT (0.45) | ACHEL3MBTL1MAPTHPGDTSHR | |
| SCHEMBL29447064 | 0.81 | ENPP2 (0.44) | ENPP2L3MBTL1MAPTHPGDTSHR | |
| SCHEMBL6600252 | 0.81 | BACE1 (0.43) | ENPP2MAPTHPGDTSHRALDH1A1 | |
| SCHEMBL20704942 | 0.81 | ENPP2 (0.44) | ENPP2L3MBTL1MAPTHPGDTSHR | |
| SCHEMBL5869062 | 0.81 | ENPP2 (0.40) | ENPP2PTPN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL29950672 | 0.81 | BACE1 (0.43) | ENPP2MAPTHPGDTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118302417-A | NLRP3 inhibitors | PTC医疗公司 | 2024-07-05 | — | — | CN | disclosed |