Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 18/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 16/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30995013 | 1.00 | F11 (0.40) | F11KLKB1CYP3A4F2F10 | |
| SCHEMBL30995030 | 0.89 | F11 (0.44) | F11KLKB1CYP3A4F2F10 | |
| SCHEMBL30995047 | 0.89 | F11 (0.44) | F11KLKB1CYP3A4F2F10 | |
| SCHEMBL30623106 | 0.85 | F11 (0.48) | F11KLKB1CYP3A4F2F10 | |
| SCHEMBL31174070 | 0.85 | F11 (0.40) | F11KLKB1CYP3A4F2F10 | |
| SCHEMBL30995016 | 0.84 | NOTUM (0.41) | F11KLKB1CYP3A4NOTUM | |
| SCHEMBL31174045 | 0.81 | F11 (0.40) | F11KLKB1CYP3A4F2F10 | |
| SCHEMBL30994987 | 0.81 | F11 (0.40) | F11KLKB1CYP3A4F2F10 | |
| SCHEMBL31174112 | 0.80 | F11 (0.41) | F11CYP2C9NOTUMGABRA2GABRB2 | |
| SCHEMBL28495547 | 0.80 | F11 (0.40) | F11KLKB1CYP3A4F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118852163-A | Macrocyclic compound containing heteroatoms, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-118126046-A | Substituted macrocyclic compound, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2024-06-04 | — | — | CN | disclosed |