Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 17/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 16/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30995013 | 0.85 | F11 (0.40) | F11KLKB1CYP3A4F2F10 | |
| SCHEMBL30995055 | 0.85 | F11 (0.40) | F11KLKB1CYP3A4F2F10 | |
| SCHEMBL30995028 | 0.85 | F11 (0.47) | F11KLKB1CYP3A4 | |
| SCHEMBL30995030 | 0.84 | F11 (0.44) | F11KLKB1CYP3A4F2F10 | |
| SCHEMBL30995047 | 0.84 | F11 (0.44) | F11KLKB1CYP3A4F2F10 | |
| SCHEMBL29697761 | 0.84 | F11 (0.49) | F11KLKB1CYP3A4F2F10 | |
| SCHEMBL21357595 | 0.84 | F11 (0.49) | F11KLKB1CYP3A4F2F10 | |
| SCHEMBL30590414 | 0.81 | F11 (0.39) | F11KLKB1CYP3A4F2F10 | |
| SCHEMBL21357414 | 0.78 | F11 (0.51) | F11KLKB1CYP3A4F2F10 | |
| SCHEMBL30995017 | 0.78 | F11 (0.48) | F11KLKB1CYP3A4F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024131841-A1 | NOVEL OXO-PYRIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 成都施贝康生物医药科技有限公司 | 2024-06-27 | — | — | WO | disclosed |
| CN-111770917-B | Process for the preparation of two compounds | 拜耳股份公司 | 2023-09-26 | — | — | CN | disclosed |