Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 9/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30995134 | 0.81 | CYP11B2 (0.46) | CYP11B2OPRM1OPRD1OPRK1CYP11B1 | |
| SCHEMBL30995235 | 0.80 | HSD17B10 (0.41) | CYP11B2CYP11B1ALDH1A1KDM4ETSHR | |
| SCHEMBL30995122 | 0.78 | KMT2A (0.54) | CYP11B2ALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL30995204 | 0.78 | CYP11B2 (0.40) | CYP11B2CYP11B1ALDH1A1ADORA2ACHRM3 | |
| SCHEMBL30995123 | 0.77 | MAPT (0.43) | CYP11B2OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL30995127 | 0.77 | HSD17B10 (0.41) | CYP11B2ALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL21771755 | 0.72 | KDM2B (0.36) | CYP11B2CYP11B1ALDH1A1KDM4ETSHR | |
| SCHEMBL21771753 | 0.72 | KDM4E (0.39) | CYP11B2ALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL21771754 | 0.72 | KDM4E (0.39) | CYP11B2ALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL30995226 | 0.71 | CYP11B2 (0.53) | CYP11B2CYP11B1ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530160-A | Aromatic heterocyclic compound, preparation method and application thereof | 上海翊石医药科技有限公司 | 2024-08-23 | — | — | CN | disclosed |