Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 4/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CCR9 | P51686 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30995123 | 0.95 | MAPT (0.43) | CYP11B2MAPTTDP1SMN1; SMN2LMNA | |
| SCHEMBL12490981 | 0.83 | NOD2 (0.55) | SMN1; SMN2NOD2NOD1MEN1KMT2A | |
| SCHEMBL30995153 | 0.82 | CYP11B2 (0.48) | CYP11B2TSHRCYP11B1CCR9KDM4E | |
| SCHEMBL327634 | 0.82 | MAPT (0.51) | MAPTTDP1SMN1; SMN2LMNATSHR | |
| SCHEMBL30995226 | 0.81 | CYP11B2 (0.53) | CYP11B2TSHRCYP11B1CCR9KDM4E | |
| SCHEMBL30995158 | 0.81 | CYP11B2 (0.43) | CYP11B2TSHRCYP11B1KDM4EOPRM1 | |
| SCHEMBL7485099 | 0.81 | MAPT (0.56) | CYP11B2MAPTTDP1SMN1; SMN2LMNA | |
| SCHEMBL30995170 | 0.80 | MAPT (0.48) | MAPTTDP1SMN1; SMN2LMNATSHR | |
| SCHEMBL30995228 | 0.78 | NOD2 (0.41) | SMN1; SMN2NOD2NOD1MEN1KMT2A | |
| SCHEMBL30995157 | 0.78 | NOD2 (0.53) | SMN1; SMN2NOD2NOD1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530160-A | Aromatic heterocyclic compound, preparation method and application thereof | 上海翊石医药科技有限公司 | 2024-08-23 | — | — | CN | disclosed |