Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30995242 | 1.00 | ALOX15 (0.52) | ALOX15KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL23049623 | 0.89 | ALOX15 (0.55) | ALOX15KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL30995141 | 0.86 | KDM4E (0.50) | ALOX15KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL23148030 | 0.86 | KDM4E (0.50) | ALOX15KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL1093057 | 0.86 | ALOX15 (0.62) | ALOX15KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL30695188 | 0.86 | ALOX15 (0.62) | ALOX15KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL31651607 | 0.84 | ULK1 (0.47) | GRIN1EIF4A3 | |
| SCHEMBL20536009 | 0.84 | ULK1 (0.47) | GRIN1EIF4A3 | |
| SCHEMBL23049687 | 0.83 | ALOX15 (0.52) | ALOX15KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL4037610 | 0.83 | KDM4E (0.48) | ALOX15KDM4EALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530160-A | Aromatic heterocyclic compound, preparation method and application thereof | 上海翊石医药科技有限公司 | 2024-08-23 | — | — | CN | disclosed |