Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GALR2 | O43603 | 1/20 | 0.34 |
| ▸ | GALR1 | P47211 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.32 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29319738 | 0.90 | GPR119 (0.38) | GPR119TLR9LMNAMAPTSMN1; SMN2 | |
| SCHEMBL30995283 | 0.90 | GPR119 (0.38) | GPR119TLR9LMNAMAPTSMN1; SMN2 | |
| SCHEMBL27213776 | 0.90 | TLR9 (0.37) | GPR119TLR9LMNAMAPTSMN1; SMN2 | |
| SCHEMBL30995287 | 0.90 | TLR9 (0.37) | GPR119TLR9LMNAMAPTSMN1; SMN2 | |
| SCHEMBL29318390 | 0.90 | TLR9 (0.37) | GPR119TLR9LMNAMAPTSMN1; SMN2 | |
| SCHEMBL30995325 | 0.86 | TLR9 (0.37) | GPR119TLR9LMNAMAPTSMN1; SMN2 | |
| SCHEMBL30849234 | 0.81 | CA2 (0.32) | LMNAMAPTSMN1; SMN2CA2NPC1 | |
| SCHEMBL29318403 | 0.81 | PDE5A (0.33) | MAPTCA2 | |
| SCHEMBL30849250 | 0.81 | PDE5A (0.33) | MAPTCA2 | |
| SCHEMBL27213705 | 0.81 | PDE5A (0.33) | MAPTCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4634169-A1 | 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF | Pfizer Inc. (US) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024127297-A1 | 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF | PFIZER INC. (US) | 2024-06-20 | — | — | WO | disclosed |