SCHEMBL30995346

SCHEMBL30995346

COc1ccc(COc2c(F)cc(C(=O)NCC34CCC(c5noc(-c6ccnc(N7CCN(CCCc8ccc9c(c8)n(C)c(=O)n9C8CCC(=O)NC8=O)CC7)n6)n5)(CC3)CC4)c(F)c2F)cc1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 4/20 0.34
CRBN Q96SW2 4/20 0.34
EGFR P00533 6/20 0.33
ERBB3 P21860 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29319381 1.00 DDB1 (0.34) DDB1CRBNEGFRERBB3
SCHEMBL29320673 0.91 DDB1 (0.37) DDB1CRBNEGFR
SCHEMBL30994986 0.91 DDB1 (0.37) DDB1CRBNEGFR
SCHEMBL29317577 0.91 DDB1 (0.37) DDB1CRBNEGFR
SCHEMBL29320544 0.91 DDB1 (0.36) DDB1CRBNEGFR
Hydrochloric Acid SCHEMBL30970028 0.91 DDB1 (0.36) DDB1CRBNEGFR
SCHEMBL30995457 0.89 CRBN (0.34) DDB1CRBNEGFRERBB3
SCHEMBL29319779 0.89 CRBN (0.34) DDB1CRBNEGFRERBB3
Trifluoroacetic Acid SCHEMBL30970035 0.88 DDB1 (0.34) DDB1CRBNEGFR
SCHEMBL29320147 0.88 DDB1 (0.38) DDB1CRBNEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634169-A1 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF Pfizer Inc. (US) 2025-10-22 EP disclosed
WO-2024127297-A1 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF PFIZER INC. (US) 2024-06-20 WO disclosed