Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 4/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.34 |
| ▸ | EGFR | P00533 | 6/20 | 0.33 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30995346 | 1.00 | DDB1 (0.34) | DDB1CRBNEGFRERBB3 | |
| SCHEMBL29320673 | 0.91 | DDB1 (0.37) | DDB1CRBNEGFR | |
| SCHEMBL30994986 | 0.91 | DDB1 (0.37) | DDB1CRBNEGFR | |
| SCHEMBL29317577 | 0.91 | DDB1 (0.37) | DDB1CRBNEGFR | |
| SCHEMBL29320544 | 0.91 | DDB1 (0.36) | DDB1CRBNEGFR | |
| Hydrochloric Acid SCHEMBL30970028 | 0.91 | DDB1 (0.36) | DDB1CRBNEGFR | |
| SCHEMBL30995457 | 0.89 | CRBN (0.34) | DDB1CRBNEGFRERBB3 | |
| SCHEMBL29319779 | 0.89 | CRBN (0.34) | DDB1CRBNEGFRERBB3 | |
| Trifluoroacetic Acid SCHEMBL30970035 | 0.88 | DDB1 (0.34) | DDB1CRBNEGFR | |
| SCHEMBL29320147 | 0.88 | DDB1 (0.38) | DDB1CRBNEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | PFIZER INC. (US) | 2024-07-18 | — | — | US | disclosed |
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | PFIZER INC. (US) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | HSD17B13, HSD17B3, HSD17B1 | DDB1 294/4885CRBN 1994/4885EGFR 2716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.