Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 6/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.39 |
| ▸ | JAK1 | P23458 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23120739 | 0.88 | GLA (0.39) | CRBNCHRM2CHRM3JAK1NAMPT | |
| SCHEMBL29606453 | 0.88 | GLA (0.39) | CRBNCHRM2CHRM3JAK1NAMPT | |
| SCHEMBL21409346 | 0.82 | GABRD (0.57) | CRBNDDB1NAMPTGABRDGABRA1 | |
| Hydrochloric Acid SCHEMBL31138067 | 0.81 | GABRD (0.56) | CRBNDDB1NAMPTGABRDGABRA1 | |
| SCHEMBL23121068 | 0.78 | EPHX2 (0.41) | CRBNCHRM2CHRM3EPHX2 | |
| SCHEMBL19226413 | 0.77 | GABRD (0.60) | CHRM2CHRM3JAK1NAMPTHPGD | |
| SCHEMBL30995421 | 0.77 | CRBN (0.38) | CRBNDDB1GFERHPGDGABRD | |
| SCHEMBL29319113 | 0.77 | CRBN (0.38) | CRBNDDB1GFERHPGDGABRD | |
| Hydrochloric Acid SCHEMBL30970066 | 0.76 | CRBN (0.37) | CRBNDDB1GFERHPGDGABRD | |
| SCHEMBL23122011 | 0.75 | GFER (0.44) | CRBNDDB1GFERHPGDGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4634169-A1 | 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF | Pfizer Inc. (US) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024127297-A1 | 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF | PFIZER INC. (US) | 2024-06-20 | — | — | WO | disclosed |