Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 2/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5857975 | 1.00 | GAA (0.41) | GAAL3MBTL1CHRNB2CHRNA4CASP6 | |
| SCHEMBL14993059 | 0.93 | GAA (0.41) | GAAL3MBTL1CHRNB2CHRNA4CASP6 | |
| SCHEMBL19914276 | 0.84 | L3MBTL1 (0.46) | GAAL3MBTL1CHRNB2CHRNA4LRRK2 | |
| SCHEMBL10885994 | 0.81 | TERT (0.45) | GAAL3MBTL1CHRNB2CHRNA4MAPT | |
| SCHEMBL2493716 | 0.81 | L3MBTL1 (0.43) | GAAL3MBTL1CHRNB2CHRNA4LRRK2 | |
| SCHEMBL25105686 | 0.78 | GAA (0.41) | GAAL3MBTL1CHRNB2CHRNA4MAPT | |
| SCHEMBL720889 | 0.78 | L3MBTL1 (0.41) | GAAL3MBTL1CHRNB2CHRNA4LRRK2 | |
| SCHEMBL5857363 | 0.78 | L3MBTL1 (0.41) | GAAL3MBTL1CHRNB2CHRNA4LRRK2 | |
| SCHEMBL19914262 | 0.78 | L3MBTL1 (0.41) | GAAL3MBTL1CHRNB2CHRNA4LRRK2 | |
| SCHEMBL31344803 | 0.78 | MAPT (0.41) | GAAL3MBTL1CHRNB2CHRNA4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530224-A | Pyrimidinone compound and application thereof | 深圳安泰维生物医药有限公司 | 2024-08-23 | — | — | CN | disclosed |