SCHEMBL30995657

SCHEMBL30995657

CCOC(=O)c1cc(Br)c(C)c2c1CCC2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.44
BRD4 O60885 1/20 0.43
TSHR P16473 1/20 0.43
KDM4E B2RXH2 4/20 0.43
RXFP1 Q9HBX9 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
MAPT P10636 4/20 0.43
ALDH1A1 P00352 3/20 0.43
GAA P10253 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
POLB P06746 1/20 0.43
HPGD P15428 1/20 0.43
RECQL P46063 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA7 P43166 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20558603 1.00 ACHE (0.44) ACHEBRD4TSHRKDM4ERXFP1
SCHEMBL19124104 0.97 KDM4E (0.45) ACHEBRD4TSHRKDM4ERXFP1
SCHEMBL30995620 0.83 CA12 (0.49) ACHEBRD4TSHRKDM4EMAPT
SCHEMBL27353018 0.83 CA12 (0.49) ACHEBRD4TSHRKDM4EMAPT
SCHEMBL19124079 0.80 GAA (0.42) KDM4ERXFP1NPSR1ALDH1A1GAA
SCHEMBL19125182 0.80 ALDH1A1 (0.40) ACHETSHRKDM4ENPSR1MAPT
SCHEMBL4627413 0.77 TSHR (0.57) TSHRKDM4ERXFP1NPSR1MAPT
SCHEMBL71222 0.77 TSHR (0.57) TSHRKDM4ERXFP1NPSR1MAPT
SCHEMBL20558628 0.77 GAA (0.42) KDM4ERXFP1NPSR1ALDH1A1GAA
SCHEMBL4626852 0.76 TSHR (0.52) TSHRKDM4ERXFP1NPSR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634152-A1 NOVEL BICYCLIC-CARBOXAMIDE COMPOUNDS USEFUL AS PESTICIDES Syngenta Crop Protection AG (CH) 2025-10-22 EP disclosed
WO-2024126650-A1 NOVEL BICYCLIC-CARBOXAMIDE COMPOUNDS USEFUL AS PESTICIDES SYNGENTA CROP PROTECTION AG (CH) 2024-06-20 WO disclosed