Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25224525 | 1.00 | PTPN1 (0.43) | PTPN1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL25702940 | 0.82 | GABRP (0.62) | PTPN1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL642295 | 0.81 | PTPN1 (0.46) | PTPN1ALDH1A1MAPTKMT2AMEN1 | |
| Bromide SCHEMBL16754110 | 0.81 | GABRP (0.61) | PTPN1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL12410963 | 0.77 | SMN1; SMN2 (0.54) | ALDH1A1MAPTKMT2AMEN1GABRP | |
| SCHEMBL398966 | 0.77 | GABRP (0.66) | ALDH1A1KMT2AMEN1GABRPGABRD | |
| SCHEMBL29524409 | 0.77 | GABRP (0.66) | ALDH1A1KMT2AMEN1GABRPGABRD | |
| SCHEMBL403869 | 0.77 | GABRP (0.46) | ALDH1A1MAPTKMT2AMEN1GABRP | |
| SCHEMBL30996511 | 0.77 | SMN1; SMN2 (0.54) | ALDH1A1MAPTKMT2AMEN1GABRP | |
| SCHEMBL18397167 | 0.76 | NNMT (0.63) | PTPN1ALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118369317-A | Melanocortin 4 receptor antagonists and uses thereof | 辉瑞大药厂 | 2024-07-19 | — | — | CN | disclosed |