Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Chlorobutanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.83 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorobutanol SCHEMBL28216046 | 0.92 | — | — | |
| Chlorobutanol SCHEMBL5719643 | 0.91 | THRB (1.00) | THRBTSHRLMNA | |
| Chlorobutanol SCHEMBL1040 | 0.91 | — | — | |
| Chlorobutanol SCHEMBL27496467 | 0.87 | — | — | |
| Chlorobutanol SCHEMBL466638 | 0.87 | THRB (0.91) | THRBTSHRLMNA | |
| Chlorobutanol SCHEMBL27945422 | 0.87 | — | — | |
| Chlorobutanol SCHEMBL7670584 | 0.87 | THRB (0.91) | THRBTSHRLMNA | |
| Chlorobutanol SCHEMBL9242282 | 0.87 | — | — | |
| Chlorobutanol SCHEMBL11215994 | 0.87 | THRB (0.91) | THRBTSHRLMNA | |
| Chlorobutanol SCHEMBL1043683 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803906-B2 | Composition comprising an angiogenesis related protein | GENE SIGNAL INTERNATIONAL SA (CH) | 2010-09-28 | — | — | US | claimed |